Recombinant Rat HB-EGF protein CD00118 from Bioassay Technology Laboratory

Description

Heparin-binding epidermal growth factor (HB-EGF)-like growth factor (EGF) is found in cerebral neurons. Its expression is increased after hypoxic or ischemic injury, which also stimulates neurogenesis. HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation and wound healing, and in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. HB-EGF is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues. In addition, it shares about 73 % and 76 % a.a. sequence identity with Mouse and rat HB-EGF

Product Specs
ItemRecombinant Rat HB-EGF protein
CompanyBioassay Technology Laboratory
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberCD00118
Quantity10 ug
Molecular WeightApproximately 9.7 kDa, a single non-glycosylated polypeptide chain containing 86 amino acids
HostEscherichia coli
FormatLyophilized from a 0.2 µm filtered concentrated solution in PBS, 300 mM NaCl, pH 7.4, 5 % trehalose
Research AreaImmunology
Purity> 95 % by SDS-PAGE and HPLC analyses
ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using Mouse Balb/c 3T3 cells is less than 1 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg
NCBI Full Gene Nameheparin-binding EGF-like growth factor
NCBI Gene AliasesDtr, GFHB, Hb-egf, Hegfl